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Anticholinergic/sedative combos decreases levels of promethazine by inhibition of GI absorption. Applies only to oral type of both equally agents. Use Warning/Monitor. cimetidine will increase the degree or result of codeine by affecting hepatic enzyme CYP2D6 metabolism. Use Warning/Watch. Helps prevent conversion of codeine to its active metabolite morphine. Due https://wockusa.com/product/actavis-promethazine-codeine/

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