2. Histamine Receptor Antagonism: Some sedatives, for instance antihistamines, exert their sedative effects by blocking histamine receptors in the brain, specifically H1 receptors. Histamine plays a role in wakefulness and arousal, so blocking its effects encourages sedation and sleepiness. Dietary supplements: A number of supplements — together with valerian https://arthurxqgvk.targetblogs.com/33561448/fast-acting-sedative-drugs-how-they-function-safety-tips